Publications

#: equally contributed; *: corresponding author 

2024

17. Jinta Asami†, Jae-Hyun Park†, Yayoi Nomura†, Chisa Kobayashi†, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi*, Sam-Yong Park*, Norimichi Nomura* & Umeharu Ohto* (2024) Structural basis of hepatitis B virus receptor binding. Nature Structural & Molecular Biology


2023

16.  Jae-Hyun Park†, Kouki Kawakami†, Naito Ishimoto, Tatsuya Ikuta, Mio Ohki, Toru Ekimoto, Mitsunori Ikeguchi, Dong-Sun Lee, Young-Ho Lee, Jeremy R.H. Tame, Asuka Inoue*, Sam-Yong Park* (2023) Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nature Communications

15.  Naito Ishimoto†, Jae-Hyun Park†, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R. H. Tame, Asuka Inoue, Sam-Yong Park* (2023) Structural basis of CXC chemokine receptor 1 ligand binding and activation. Nature Communications


2022

14. Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, Mizuki Oshima, Masamichi Muramatsu, Takaji Wakita, Mikako Shirouzu, Kehond Liu, Tomoko Uemura, Norimichi Nomura, So Iwata, Koichi Watashi, Jeremy R. H. Tame, Tomoyuki Nishizawa, Weontae Lee*, Sam-Yong Park* (2022) Structural insights into the HBV receptor and bile acid transporter NTCP. Nature

13. Yunseok Heo, Inhwan Lee, Sunjin Moon, Ji-Hye Yun, Eun Yu Kim, Sam-Yong Park, Jae-Hyun Park, Woo Taek Kim*, Weontae Lee* (2022) Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain Molecules


2021

12.  Ji-Hye Yun†, Xuanxuan Li†, Jianing Yue, Jae-Hyun Park, Zeyu Jin, Chufeng Li, Hao Hu, Yingchen Shi, Suraj Pandey, Sergio Carbajo, Sebastien Boutet, Mark S. Hunter, Mengning Liang, Raymond G. Sierra, Thomas J. Lane, Liang Zhou, Uwe Weierstall, Nadia A. Zatsepin, Mio Ohki, Jeremy R. H. Tame, Sam-Yong Park, John C. H. Spence, Wenkai Zhang, Marius Schmidt, Weontae Lee*, Haiguang Liu* (2021) Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser. Proceedings of the National Academy of Sciences of the United States of America

11.  Jeongmin Han†, Taehee Kim†, Sunjin Moon, Jae-Hyun Park, Wonbin Lee, Yoon-joo Ko, Kyoung-Seok Ryu, Ji-Hye Yun*, Weontae Lee* (2021) NMR spectroscopy uncovers direct interaction between BAF60A and p53. Biochemical and Biophysical Research Communications



2020

10.  Ji-Hye Yun†, Mio Ohki†, Jae-Hyun Park, Naito Ishimoto, Ayana Sato-Tomita, Wonbin Lee, Zeyu Jin, Jeremy R. H. Tame, Naoya Shibayama, Sam-Yong Park*, Weontae Lee*, (2020) Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family. Science Advances

9.     Yunseok Heo, Jae-Hyun Park, Jongmin Kim, Jeongmin Han, Ji-Hye Yun*, Weontae Lee* (2020) Crystal structure of the HMG domain of human BAF57 and its interaction with four-way junction DNA. Biochemical and Biophysical Research Communications

8.     Pankaj Attri†*, Jae-Hyun Park, Joey De Backer, Myeongkyu Kim, Ji-Hye Yun, Yunseok Heo, Sylvia Dewilde, Masaharu Shiratani, Eun Ha Choi, Weontae Lee*, Annemie Bogaerts (2020) Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study. International Journal of Biological Macromolecules

7.   Ji-Hye Yun†, Jae-Hyun Park†, Zeyu Jin†, Mio Ohki, Yang Wang, Cecylia Severin Lupala, Haigunag Liu, Sam-Yong Park, Weontae Lee*., (2020) Structure-Based Functional Modification Study of a Cyanobacterial Chloride Pump for Transporting Multiple Anions. Journal of Molecular Biology

6.    Jeongmin Han†, Iktae Kim†, Jae-Hyun Park, Ji-Hye Yun, Keehyoung Joo, Taehee Kim, Gye-Young Park, Kyoung-Seok Ryu, Yoon-Joo Ko, Kenji Mizutani, Sam-Young Park, Rho Hyun Seong, Jooyoung Lee*, Jeong-Yong Suh*, Weontae Lee* (2020) A coil-to-helix transition serves as a binding motif for hSNF5 and BAF155 interaction. International Journal of Molecular Sciences


2019

5.    Jae-Hyun Park†, Ji-Hye Yun†, Yingchen Shi, Jeongmin Han, Xuanxuan Li, Zeyu Jin, Taehee Kim, Jaehyun Park, Sehan Park, Haiguang Liu*, Weontae Lee* (2019) Non-Cryogenic structure and dynamics of HIV-1 integrase catalytic core domain by X-ray free-electron lasers. International Journal of Molecular Sciences

4.   Yang Wang†, Jae-Hyun Park†, Cecylia Severin Lupala, Ji-Hye Yun, Zeyu Jin, Lanqing Huang, Xuanxuan Li, Leihan Tang, Weontae Lee*, Haiguang Liu* (2019) Computer aided protein engineering to enhance the thermo-stability of CXCR1-T4 lysozyme complex. Scientific Reports

3.   Ji-Hye Yun†, Xuanxuan Li†, Jae-Hyun Park, Yang Wang, Mio Ohki, Zeyu Jin, Wonbin Lee, SamYong Park, Hao Hu, Chufeng Li, Nadia Zatsepin, Mark S. Hunter, Raymond G. Sierra, Jake Koralek, Chun Hong Yoon, Hyun-Soo Cho, Uwe Weierstall, Leihan Tang, Haiguang Liu*, Weontae Lee* (2019) Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency. Journal of Biological Chemistry


2018

2.    Yang Wang, Cecylia Severin Lupala, Ting Wang, Xuanxuan Li, Ji-Hye Yun, Jae-Hyun Park, Zeyu Jin, Weontae Lee, Leihan Tan, Haiguang Liu* (2018) A computational study of the chemokine receptor CXCR1 bound with interleukin-8. Chinese Physics B


2014

1.  Ji-Hye Yun, Kuglae Kim, Youngjin Jung, Jae-Hyun Park, Hyun-Soo Cho, Weontae Lee* (2014) Co-expression of human agouti-related protein enhances expression and stability of human melanocortin-4 receptor. Biochemical and Biophysical Research Communications